2000 Schedule Wesley
| Overall | Pct. | Conf. | Pct. | Streak | Home | Away | Neutral |
| 8-2 | .800 | 3-0 | 1.000 | Lost 1 | 3-0 | 5-2 | 0-0 |
| Date | Opponent | Result | Time/Status | Links |
| Sep. 9 | at Rowan | L, 42-32 | Final | |
| Sep. 16 | Mount Ida | Cancelled | ||
| Sep. 23 | at Kean | W, 30-15 | Final | |
| Sep. 30 | at Greensboro | W, 61-21 | Final | |
| Oct. 7 | at Frostburg State * | W, 24-10 | Final | |
| Oct. 14 | Newport News | W, 68-0 | Final | |
| Oct. 21 | Methodist | W, 48-6 | Final | |
| Oct. 28 | at Salisbury * | W, 33-29 | Final | |
| Nov. 4 | at Chowan * | W, 49-10 | Final | |
| Nov. 11 | Ferrum | W, 27-24 | Final | |
| Nov. 18 | at Trinity (Texas) | L, 21-3 | Final | |
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