2010 Schedule McDaniel
| Overall | Pct. | Conf. | Pct. | Streak | Home | Away | Neutral |
| 5-5 | .500 | 4-5 | .444 | Lost 1 | 3-2 | 2-3 | 0-0 |
| Date | Opponent | Result | Time/Status | Links |
| Sep. 4 | at Juniata * | W, 3-0 | Final | BX BX |
| Sep. 11 | Moravian * | W, 13-10 | Final | BX BX |
| Sep. 18 | at Catholic | W, 24-14 | Final | BX RC |
| Sep. 25 | Dickinson * | L, 41-16 | Final | BX BX |
| Oct. 9 | Susquehanna * | W, 35-0 | Final | BX BX BX RC |
| Oct. 16 | Muhlenberg * | L, 29-0 | Final | BX BX |
| Oct. 23 | at Ursinus * | L, 43-18 | Final | BX BX BX BX RC |
| Oct. 30 | at Franklin and Marshall * | L, 31-28 | Final | BX BX BX BX RC P |
| Nov. 6 | Gettysburg * | W, 36-30 | Final - 3OT | BX BX BX RC |
| Nov. 13 | at Johns Hopkins * | L, 34-10 | Final | BX BX RC |
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