2022 Division III football schedule Nebraska Wesleyan
| Overall | Pct. | Conf. | Pct. | Streak | Home | Away | Neutral |
| 1-9 | .100 | 0-8 | .000 | Lost 9 | 0-4 | 1-5 | 0-0 |
| Date | Opponent | Result | Time/Status | Links |
| Sep. 3 | at Eureka | W, 31-6 | Final | BX P |
| Sep. 10 | at Mayville St. | L, 55-48 | Final - OT | |
| Sep. 17 | Dubuque * | L, 48-34 | Final | BX RC |
| Sep. 24 | at Loras * | L, 49-31 | Final | BX |
| Oct. 1 | Central * | L, 58-0 | Final | BX RC |
| Oct. 15 | at Wartburg * | L, 65-0 | Final | BX |
| Oct. 22 | Buena Vista * | L, 42-25 | Final | |
| Oct. 29 | at Simpson * | L, 74-41 | Final | BX |
| Nov. 5 | Coe * | L, 34-14 | Final | BX |
| Nov. 12 | at Luther * | L, 35-28 | Final | |
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