2000 Schedule Adrian
| Overall | Pct. | Conf. | Pct. | Streak | Home | Away | Neutral |
| 2-8 | .200 | 1-4 | .200 | Lost 4 | 2-3 | 0-5 | 0-0 |
| Date | Opponent | Result | Time/Status | Links |
| Sep. 9 | at Baldwin-Wallace | L, 49-3 | Final | |
| Sep. 16 | Defiance | L, 28-7 | Final | |
| Sep. 23 | at Carthage | L, 21-3 | Final | |
| Sep. 30 | at Thomas More | L, 20-6 | Final | |
| Oct. 7 | Wisconsin Lutheran | W, 13-12 | Final | BX |
| Oct. 14 | Olivet * | W, 23-14 | Final | |
| Oct. 21 | at Albion * | L, 56-10 | Final | |
| Oct. 28 | Hope * | L, 33-6 | Final | |
| Nov. 4 | at Alma * | L, 26-19 | Final | |
| Nov. 11 | Kalamazoo * | L, 24-10 | Final | |
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