2000 Schedule Mount St. Joseph
| Overall | Pct. | Conf. | Pct. | Streak | Home | Away | Neutral |
| 2-8 | .200 | 1-6 | .143 | Lost 6 | 1-4 | 1-4 | 0-0 |
| Date | Opponent | Result | Time/Status | Links |
| Sep. 2 | at Muskingum | L, 42-14 | Final | |
| Sep. 9 | Otterbein | L, 35-0 | Final | |
| Sep. 16 | at Kalamazoo | W, 24-19 | Final | |
| Sep. 23 | Hiram * | W, 26-21 | Final | |
| Sep. 30 | Defiance * | L, 28-14 | Final | |
| Oct. 7 | at Bluffton * | L, 33-0 | Final | |
| Oct. 14 | at Anderson * | L, 19-17 | Final | |
| Oct. 21 | Hanover * | L, 55-12 | Final | |
| Oct. 28 | at Manchester * | L, 36-14 | Final | |
| Nov. 4 | Franklin * | L, 58-21 | Final | |
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